VIVO: The New Standard for Patient Specific Planning of Ventricular Ablations
Prof Sabine Ernst, an electrophysiologist at Royal Brompton Hospital, London, UK, and a longtime investigator with the VIVO system, discusses her use of non-invasive 3D mapping to guide PVC ablations. She highlights the advantage of performing mapping on the ward – while patients are ambulatory and more likely to exhibit arrhythmias – which saves time and captures critical data before entering the lab. Prof Ernst notes that VIVO is particularly effective for identifying single-source PVCs, rare ectopics and arrhythmias from challenging locations like the epicardium, supporting better procedural planning and patient communication. She concludes that VIVO enables clearer risk discussions and helps manage expectations, ultimately leading to more efficient and targeted ablations.
In this video series, recorded at EHRA 2025, leading cardiologists Prof Sabine Ernst (Royal Brompton Hospital, London, UK), Dr Gábor Széplaki (Mater Private Hospital, Dublin, Ireland) and Dr Leonor Parreira (Centro Hospitalar de Setúbal, Setúbal, Portugal) share their experience of VIVO – a technology supporting optimal management of ventricular ablation patients.
VIVO™ (View Into Ventricular Onset) is a non-invasive 3D cardiac mapping system designed to assist EPs in the precise localisation of ventricular arrhythmias, such as premature ventricular contractions and ventricular tachycardia, prior to ablation procedures.
Here, the faculty share their insights on the best setting for VIVO’s use, how it supports both HCP and patients in clinical practice, whilst they also consider the wider role of non-invasive mapping in the future.

More from this programme
Part 1
Perspectives from Prof Sabine Ernst – VIVO: The New Standard for Patient Specific Planning of Ventricular Ablations
Prof Sabine Ernst, an electrophysiologist at Royal Brompton Hospital, London, UK, and a longtime investigator with the VIVO system, discusses her use of non-invasive 3D mapping to guide PVC ablations. She highlights the advantage of performing mapping on the ward – while patients are ambulatory and more likely to exhibit arrhythmias – which saves time and captures critical data before entering the lab. Prof Ernst notes that VIVO is particularly effective for identifying single-source PVCs, rare ectopics and arrhythmias from challenging locations like the epicardium, supporting better procedural planning and patient communication. She concludes that VIVO enables clearer risk discussions and helps manage expectations, ultimately leading to more efficient and targeted ablations.
Part 2
Perspectives from Dr Leanor Parreira – VIVO: The New Standard for Patient Specific Planning of Ventricular Ablations
Dr Leonor Parreira, an electrophysiologist in Lisbon, Portugal, outlines the advantages and future potential of the VIVO non-invasive mapping system for ventricular ablation. Primarily used pre-procedurally, VIVO helps Dr Parreira identify arrhythmia origins, enabling faster, more precise procedures and sometimes avoiding unnecessary ones – especially in patients with low PVC burden or unstable arrhythmias. It’s also effective in complex cases with multiple morphologies or brief episodes of ventricular tachycardia. Dr Parreira envisions a shift toward fully non-invasive treatments, with VIVO playing a key role in both current workflows and emerging approaches like stereotactic radiotherapy and substrate-based ablation.
Part 3
Perspectives from Dr Gabor Szeplaki – VIVO: The New Standard for Patient Specific Planning of Ventricular Ablations
Dr Gabor Szeplaki, an electrophysiology at Mather Private Hospital in Dublin, Ireland, discusses the value of the non-invasive VIVO mapping system for pre-procedural premature ventricular contraction (PVC) mapping. By combining ECG data with a CT scan, the system helps Dr Szeplaki accurately localise the PVC source, which is particularly useful when PVCs are infrequent or hard to detect during the procedure itself. This pre-procedural insight improves efficiency, safety, and outcomes, especially in challenging cases. Dr Szeplaki highlights the benefit of integrating this data with 3D mapping and intracardiac echo during the procedure, and notes that early detection of complex or risky PVC sites may even inform the decision to postpone or avoid invasive treatment.
Faculty Biographies

Sabine Ernst
Consultant Cardiologist
Prof Sabine Ernst is a cardiac electrophysiologist with special expertise in complex arrhythmias, such as atrial fibrillation and ventricular arrhythmia in both paediatric and adult patients. She is a Consultant Cardiologist at NIHR Cardiovascular Biomedical Research Unit, Royal Brompton and National Heart and Lung Institute, Imperial College London & Harefield NHS Foundation Trust. She has been a Reader at Imperial College London.
Prof Ernst is a cardiac electrophysiologist with special expertise in: complex arrhythmias, atrial fibrillation, ventricular arrhythmia in both paediatric and adult patients. She is one of the pioneers of remote magnetic navigation. Prof Ernst has established this technique from its initiation to it becoming a clinical routine procedure using state-of-the-art equipment, including advanced 3D-mapping techniques. Patients with congenital heart disease, complex anatomy and arrhythmias especially benefit from this technique and form a…