Dr Bradley Knight (Northwestern University Feinberg School of Medicine / Northwestern Medicine Bluhm Cardiovascular Institute, Chicago, IL, US) joins us to discuss the clinical role of the Sphere 9 Pulse Field System and what its adoption may mean for catheter ablation practice in atrial fibrillation.

Interview Questions:

1. How has the Sphere‑9 single‑catheter setup changed your usual AF workflow?  
2. What impact has it had on procedure time, catheter exchanges, and lab efficiency?  
3. Has it reduced fluoroscopy use, and what makes that possible?  
4. In persistent AF or non‑PV targets, how does a single catheter affect your lesion strategy?  
5. Which patients are best suited for this workflow, and when do you avoid it?  
6. What were your key lessons on team training and lab setup when adopting it?  
7. How do you see focal PFA and single‑shot PFA coexisting in the next few years?  
8. Critics say single‑catheter workflows oversimplify complex AF—how does your experience support or challenge that view?

Recorded on-site at HRS 2026, Chicago.

Editor: Jordan Rance 

Videographer: Oliver Miles

Support: This is an independent interview produced by Radcliffe Cardiology.