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PFA in Persistent AF – Navigating Real-World Safety Concerns

Published: 13 Apr 2026

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EHRA 2026, Paris — Dr Marco Schiavone (Centro Cardiologico Monzino IRCCS, Milan, Italy) walks through a real-world case from his clinical practice, shining a light on the safety considerations that emerge when pulsed field ablation is applied in persistent AF — a population where procedural complexity and the stakes of adverse events are inherently higher.

Drawing on instructive cases encountered at the frontier of PFA adoption, Dr Schiavone unpacks the mechanisms behind key safety signals, how they presented, and how they were managed — offering practical, experience-driven guidance for electrophysiologists expanding their PFA practice into more challenging patient territory.

Recorded at EHRA 2026, Paris.
Editors: Jordan Rance
Videographer: David Ben-Harosh
Support: This is an independent video produced by Radcliffe Cardiology.

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