EHRA 2026, Paris — Prof Reza Wakili (University Hospital Frankfurt, Frankfurt, Germany) joins us for an expert discussion on the practical integration of pulsed field ablation into modern AF ablation workflows, exploring how this transformative energy modality is reshaping the way electrophysiologists approach rhythm control across the full spectrum of AF.

As PFA moves rapidly from early adoption into mainstream practice, Prof Wakili reflects on the technical, procedural, and organisational considerations that determine how successfully centres can embed this technology — and what it means for patient outcomes at scale.

Interview Questions:

1. How has the introduction of PFA changed the way you think about AF ablation, and where does it sit within your current workflow?
2. What are the key practical considerations when transitioning a centre from radiofrequency or cryoablation to PFA — in terms of training, infrastructure, and case selection?
3. How are you approaching patient selection for PFA — are there specific profiles where you favour it over established energy sources?
4. PFA is increasingly being used beyond paroxysmal AF into persistent and long-standing persistent disease — how are you navigating that evolution in your practice?
5. What does the evidence base currently tell us about PFA's safety profile, and are there any remaining concerns you are watching closely?
6. How is PFA influencing thinking around repeat procedures and the management of AF recurrence post-ablation?
7. Looking at the broader workflow picture, how do you see PFA reshaping the EP lab — in terms of procedure times, team dynamics, and resource planning?
8. What are your key take-home messages for electrophysiologists at various stages of integrating PFA into their practice?

Recorded at EHRA 2026, Paris.

Editors: Jordan Rance
Videographer: David Ben-Harosh, Oliver Miles

Support: This is an independent interview produced by Radcliffe Cardiology.