Late-Breaking Clinical Trials and Science to be Presented at Heart Rhythm 2025
SOURCE: Heart Rhythm 2025
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Heart Rhythm 2025 has released its program featuring five late-breaking clinical trials and science sessions which will take place from the 25th to 27th April. The meeting is located in San Diego Convention Center, California. Access the full programme here.

 

Late-Breaking Clinical Trials and Science: Clinical Trials Updates and Registries

Friday 25th April, 11:45 – 12:45pm (PDT)

  • A Multielectrode Spherical Array Pulsed Field Ablation System to Treat Paroxysmal Atrial Fibrillation: 1-Year Outcomes of the PULSAR IDE Trial – Presented by Dr Vivek Reddy
  • Safety, Efficacy and PVI Durability of a Contact Force-Sensing Large-Tip Focal Pulsed Field Ablation Catheter Integrated With 3D Mapping to Treat Paroxysmal Atrial Fibrillation: First-in-Human Omny-IRE 3-Month Results – Presented by Dr Mattias Duytschaever
  • Left Bundle Branch Area Pacing Compared To Biventricular Pacing in Candidates for Cardiac Resynchronization Therapy – Presented by Dr Pugazhendhi Vijayaraman
  • Atrial Fibrillation Recurrence After Left Atrial Appendage Occlusion in Patients Undergoing Atrial Fibrillation Ablation: Lessons from The OPTION Trial – Presented by Dr Arwa Younis

 

Late-Breaking Clinical Trials and Science: Clinical Trials Updates and Registries

Friday 25th April, 14:15 – 15:15pm (PDT)

  • More Major and Lead Related Complications in Transvenous Versus Subcutaneous Defibrillator Therapy During Long-Term Follow-Up: The PRAETORIAN XL Trial – Presented by Dr Louise Olde Nordkamp
  • Evolution and Emergence of Diagnosis and Long-Term Outcome of Apparently Unexplained Cardiac Arrest – Presented by Dr Hui-Chen Han
  • Left bundle branch area placement of a novel small-diameter defibrillation lead: defibrillation results of the LEADR LBBAP clinical trial – Presented by Dr Pugazhendhi Vijayaraman
  • TRANSFORM-AF:Targeting Metabolic Therapy with GLP-1 Receptor Agonism for Secondary Prevention in Atrial Fibrillation – Presented by Dr Varun Sundaram

 

Late-Breaking Clinical Trials and Science: Clinical Trials Updates and Registries

Saturday 26th April, 09:45 – 10:45am (PDT)

  • Contemporary Outcomes of Non-Ischemic Cardiomyopathy Patients with Implanted Devices (BIO-LIBRA) – Presented by Dr Valentina Kutyifa
  • Hierarchical Physiologic Pacing to Enhance Clinical Outcomes in Conduction System Pacing – Presented by Dr Shunmuga Sundaram Ponnusamy
  • Cardiac Resynchronization Therapy Risk-stratified by CMR imaging and Optimized by LBBP: Results from long term follow-up of MADURAI LBBP study – Presented by Dr Shunmuga Sundaram Ponnusamy
  • Efficacy of Catheter Ablation for Management of Ventricular Arrhythmias in Subjects with Ischemic Cardiomyopathy- Metaanalysis of Randomized Controlled Trials Updated with the VANISH-2 Trial – Presented by Dr Girish Nair

 

Late-Breaking Clinical Trials and Science: Randomized Clinical Trials 

Saturday 26th April, 13:45 – 14:45pm (PDT)

  • Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia. The InEurHeart multicentric randomized control trial – Presented by Dr Frederic Sacher
  • Brugada Syndrome Ablation for the Prevention of VF Episodes (BRAVE) – Presented by Prof Koonlawee Nademanee
  • Transcutaneous Electrical Vagus Nerve Stimulation to Suppress Ventricular Premature Complexes (TREAT-PVC): A Randomized Clinical Trial – Presented by Dr Sunny Po

 

Late-Breaking Clinical Trials and Science: Clinical Innovations

Sunday 27th April, 11:15 – 12:15pm (PDT)

  • A Novel High-Voltage Focal Pulsed Field Ablation Catheter to Treat Scar-Related Ventricular Tachycardia: The First-in-Human VCAS Trial – Presented by Dr Vivek Reddy
  • Feasibility, Safety, and Efficacy of Compassionate Cardioneuroablation for Functional Bradycardia and Reflex Syncope: Outcomes from the Multicenter US CNA Registry – Presented by Dr Roderick Tung
  • A Leadless Pacemaker System for Left Bundle Branch Area Pacing – First in Human Experience – Presented by Dr Vivek Reddy
  • Novel Implantable Cardioverter-Defibrillator Platform with Heart Failure Therapy: Cardiac Contractility Modulation with Defibrillation – Presented by Dr Niraj Varma

 

References

Heart Rhythm 2025. Program. 2025. https://eppro01.ativ.me/src/EventPilot/php/express/web/planner.php?id=HRS25 (accessed 17 March 2025).

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